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CI994 (Tacedinaline)

CI994 (Tacedinaline)

Name: CI994 (Tacedinaline)
SKU: A11964

目录号: A11964

HDAC 抑制剂

CI994 (Tacedinaline) Chemical Structure

CAS NO. 112522-64-2

CI994 (Tacedinaline)是一种组蛋白脱乙酰基酶（HDAC）抑制剂，可在活细胞中诱导组蛋白超乙酰化。

库存：现货

规格	价格	数量
10 mg	￥ 350.00
50 mg	￥ 525.00
100 mg	￥ 770.00
10mM * 1mL in DMSO	￥ 350.00

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生物活性

CI994 (Tacedinaline)是一种组蛋白脱乙酰基酶（HDAC）抑制剂，可在活细胞中诱导组蛋白超乙酰化。

靶点信息

HDAC1 (Cell-free assay)	HDAC2	HDAC3
0.9 μM	0.9 μM	1.2 μM

溶解度 *

In vitro (25°C)	DMSO	51 mg/mL (189.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.13 mL	185.67 mL	371.33 mL
0.5 mM	7.43 mL	37.13 mL	74.27 mL
1 mM	3.71 mL	18.57 mL	37.13 mL
5 mM	0.74 mL	3.71 mL	7.43 mL

*The above data is based on the productmolecular weight 269.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11964
作用机制	Inhibitor (抑制剂)
M. Wt	269.3
Formula	C15H15N3O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	112522-64-2
Synonyms	CI-994, CI 994, Acetyldinaline, Goe 5549, G? 5549. PD 123654
SMILES	CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N