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Cilostazol是3型磷酸二酯酶（PDE3）的选择性抑制剂，IC50为0.2 μM，其治疗重点是cAMP。
靶点信息
| PDE3 | ||||
| 0.2 μM |
| In vitro | DMSO | 73 mg/mL (197.58 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 6 mg/mL (16.23 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.06 mL | 135.32 mL | 270.64 mL |
| 0.5 mM | 5.41 mL | 27.06 mL | 54.13 mL |
| 1 mM | 2.71 mL | 13.53 mL | 27.06 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
*The above data is based on the productmolecular weight 369.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10217 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 369.5 |
| Formula | C20H27N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 73963-72-1 |
| Synonyms | Pletal |
| SMILES | C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4 |
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