Cinchocaine
目录号: A17672
SChE inhibitor
Dibucaine(美国非专利药品名称)是一种酰胺类局部麻醉药。Dibucaine 可以可逆地结合并失活神经细胞膜上的钠通道。抑制钠通道可以防止神经细胞膜去极化,并抑制沿神经路径的冲动传播,从而限制神经末梢的兴奋。这将导致失去感觉。
SChE inhibitor
Discription | Dibucaine (USAN) is an amide local anesthetic. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation. | |||||
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Cell Research |
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目录号 | A17672 |
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分子式 | C20H29N3O2 |
分子量 | 343.46 |
CAS号 | 85-79-0 |
SMILES | CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC |
其他名称 | Dibucaine; Cinchocaine; Nupercainal; Nupercaine; Sovcaine; Dibucaine Base |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 59 mg/mL (171.78 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.12 mL | 145.58 mL | 291.15 mL |
0.5 mM | 5.82 mL | 29.12 mL | 58.23 mL |
1 mM | 2.91 mL | 14.56 mL | 29.12 mL |
5 mM | 0.58 mL | 2.91 mL | 5.82 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2