Cipralisant
目录号: A20061
histamine H3 receptor 拮抗剂
Cipralisant 是一种在体内具有强效和选择性的组胺H3受体拮抗剂,并且在体外是一种激动剂,其对组胺H3受体的pKi值为9.9,对大鼠组胺H3受体的Ki值为0.47 nM;Cipralisant 已进入临床试验阶段,用于治疗注意力缺陷多动障碍。
Discription | Cipralisant is a potent and selective histamine H3 receptor antagonist in vivo, and an agonist in vitro, with a pKi of 9.9 for histamine H3 receptor and a Ki of 0.47 nM for rat histamine H3 receptor; Cipralisant has entered in clinical trials for the treatment of attention-deficit hyperactivity disorder. | ||
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目录号 | A20061 |
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分子式 | C14H20N2 |
分子量 | 216.32 |
CAS号 | 213027-19-1 |
SMILES | CC(C)(C)CCC#C[C@H]1[C@H](C2=CN=CN2)C1 |
其他名称 | GT-2331, GT2331, GT 2331 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2