Cisplatin

Name: Cisplatin
SKU: A10221
Price: 175 CNY
Rating: 5 (12 reviews)

目录号: A10221

12 篇发表文献

顺铂是含铂抗癌药物类的第一种药物，现在这一类还包括卡铂和奥沙利铂。这些铂复合物在体内反应，与DNA结合并导致DNA交联，最终触发凋亡（程序性细胞死亡）。

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Grouped product items
规格	价格	库存
50mg	¥175.00	现货
100mg	¥245.00	现货
250mg	¥385.00	现货
500mg	¥630.00	现货
2g	¥1,925.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Cisplatin发表的12篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Ping Tian, .et al. , Chem Biol Drug Des, 2024, Jan;103(1):e14424 PMID: 38230774

Jintian Song, .et al. , J Cancer, 2023, May 21;14(9):1515-1530 PMID: 37325046

Huan Li, Srinivas Chatla, .et al. , Res Sq, 2023, Apr 6;rs.3.rs-2688694 PMID: 37066268

Min-Yung Kuo, .et al. , Int J Mol Sci, 2022, Dec 21;24(1):138 PMID: 36613579

Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138

RUI-NING LIANG, .et al. , Research Square, 2022, July 6th

Wei Zeng, .et al. , Exp Ther Med, 2021, May; 21(5): 424 PMID: 33747163

Yi-Ru Pan, .et al. , Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492

Amnah Alshangiti, .et al. , Neuronal Signal, 2019, 2019

Calhelha RC, .et al. , Analyst, 2017, Oct 23;142(21):4124-4141 PMID: 28991301

Pi-Lin Sung, .et al. , Oncotarget, 2016, Jan 26; 7(4): 4036-4047 PMID: 26716408

生物活性

Discription

Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).

Targets

Target	Value

产品信息

目录号	A10221
分子式	Cl2H4N2Pt
分子量	300.1
CAS号	15663-27-1
SMILES	N.N.Cl[Pt+2]Cl
其他名称	cisplatinum, CDDP, cis-diamminedichloroplatinum(II)
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	56 mg/mL (186.63 mM)
	Water	DMF: 11 mg/mL (36.66 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.32 mL	166.61 mL	333.22 mL
0.5 mM	6.66 mL	33.32 mL	66.64 mL
1 mM	3.33 mL	16.66 mL	33.32 mL
5 mM	0.67 mL	3.33 mL	6.66 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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