CJ-42794
目录号: A21948
EP4 antagonist
CJ-42794 是一种选择性前列腺素E受体亚型4(EP4)拮抗剂,能够抑制 [3H]-PGE2 与人类EP4受体的结合,平均pKi值为8.5,其结合亲和力对人类EP4受体的选择性至少是对其他人类EP受体亚型(EP1、EP2和EP3)的200倍以上。
Discription | CJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). | |||||
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Cell Research |
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目录号 | A21948 |
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分子式 | C22H17ClFNO4 |
分子量 | 413.83 |
CAS号 | 847728-01-2 |
SMILES | ClC1=CC=C(OC2=CC=C(F)C=C2)C(C(N[C@H](C3=CC=C(C(O)=O)C=C3)C)=O)=C1 |
其他名称 | CJ-042794, CJ042794, CJ 042794; CJ 42794, CJ42794 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2