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CK-636是一种Arp2/3复合抑制剂。CK-636在Arp2和Arp3之间结合，似乎阻止了Arp2和Arp3进入其活性构象。
靶点信息
| Human Arp2/3 complex | Fission yeast Arp2/3 complex | Bovine Arp2/3 complex | ||
| 4 μM | 24 μM | 32 μM |
| In vitro | DMSO | 52 mg/mL (182.85 mM) | |
| Water | Insoluble | ||
| Ethanol | 46 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.2 mL | 176 mL | 351.99 mL |
| 0.5 mM | 7.04 mL | 35.2 mL | 70.4 mL |
| 1 mM | 3.52 mL | 17.6 mL | 35.2 mL |
| 5 mM | 0.7 mL | 3.52 mL | 7.04 mL |
*The above data is based on the productmolecular weight 284.09833. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13827 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 284.09833 |
| Formula | C16H16N2OS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 442632-72-6 |
| Synonyms | CK636, CK 636 |
| SMILES | CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CS3 |
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