CL2 Linker

Name: CL2 Linker
SKU: A18388
Price: 2240 CNY
Rating: 5 (288 reviews)

目录号: A18388

cleavable ADC linker

CL2 Linker 是一种可裂解的ADC连接体。CL2-SN-38 和 CL2A-SN-38 在药物替代（约6）、细胞结合（Kd 约1.2 nM）、细胞毒性（IC50 约2.2 nM）和体外血清稳定性（t1/2 约20小时）方面相当。

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规格	价格	库存
1mg	¥2,240.00	现货
5mg	¥6,720.00	现货
10mg	¥11,200.00	现货
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Data Sheet

SDS

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生物活性

Discription

CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours).

Targets

Target	Value

产品信息

目录号	A18388
分子式	C68H103N11O22
分子量	1426.61
CAS号	2270986-66-6
SMILES	OCC(COC(N(C)CCN(C)C(OCC(C=C1)=CC=C1NC([C@H](CCCCNC(OC(C)(C)C)=O)NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN2C=C(CNC(CCCCCN3C(C=CC3=O)=O)=O)N=N2)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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