CL2A-SN-38

Name: CL2A-SN-38
SKU: A18392
Price: 525 CNY
Rating: 5 (288 reviews)

目录号: A18392

DNA Topoisomerase I 抑制剂

CL2A-SN-38 是一种药物连接物，由强效的 DNA拓扑异构酶I抑制剂 SN-38 和连接物 CL2A 组成，用于制造抗体药物偶联物（ADC）。CL2A-SN-38 对多种人类实体瘤类型提供显著且特异性的抗肿瘤效果。

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Grouped product items
规格	价格	库存
1mg	¥525.00	现货
5mg	¥1,785.00	现货
10mg	¥2,485.00	现货
25mg	¥3,465.00	现货
50mg	¥4,865.00	现货
100mg	¥6,825.00	现货
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Data Sheet

SDS

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生物活性

Discription

CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types.

Targets

Target	Value

产品信息

目录号	A18392
分子式	C73H97N11O22
分子量	1480.61
CAS号	1279680-68-0
SMILES	O=C(O[C@](C1=C(CO2)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C1)=O)(CC)C2=O)OCC6=CC=C(NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7N=NC(CNC(C8CCC(CN9C(C=CC9=O)=O)CC8)=O)=C7)=O)=O)=O)C=C6
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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