CL2A

Name: CL2A
SKU: A18396
Price: 2240 CNY
Rating: 5 (288 reviews)

目录号: A18396

L2A 是一个含有 PEG8 和三唑的可裂解复杂 PABC-肽-mc 连接体。CL2A 通过 pH敏感性 可裂解，产生旁观者效应，并通过 二硫键 在半胱氨酸残基处与抗体结合。拉贝妥珠单抗戈维替康使用了这种连接体。

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规格	价格	库存
1mg	¥2,240.00	现货
5mg	¥6,720.00	现货
10mg	¥11,200.00	现货
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Data Sheet

SDS

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生物活性

Discription	L2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker.

产品信息

目录号	A18396
分子式	C51H79N9O18
分子量	1106.22
CAS号	1846605-04-6
SMILES	O=C(NC1=CC=C(COC(O)=O)C=C1)[C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN2N=NC(CNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=C2)=O)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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