Clofarabine

Name: Clofarabine
SKU: A10228

目录号: A10228

DNA/RNA Synthesis 抑制剂

Product Citations (1)

Clofarabine Chemical Structure

CAS NO. 123318-82-1

Clofarabine具有抗肿瘤活性的第二代嘌呤核苷类似物。

库存：现货

规格	价格	数量
10 mg	￥ 350.00
50 mg	￥ 1,050.00
100 mg	￥ 1,750.00
200 mg	￥ 2,100.00
10mM * 1mL in DMSO	￥ 350.00

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生物活性

Clofarabine具有抗肿瘤活性的第二代嘌呤核苷类似物。

靶点信息

Ribonucleotide reductase
65 nM

溶解度 *

In vitro (25°C)	DMSO	55 mg/mL (181.11 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300 +1% Tween 80+ddH2O	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.93 mL	164.64 mL	329.27 mL
0.5 mM	6.59 mL	32.93 mL	65.85 mL
1 mM	3.29 mL	16.46 mL	32.93 mL
5 mM	0.66 mL	3.29 mL	6.59 mL

*The above data is based on the productmolecular weight 303.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10228
作用机制	Inhibitor (抑制剂)
M. Wt	303.7
Formula	C10H11ClFN5O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	123318-82-1
Synonyms	Clolar, Evoltra
SMILES	C1=NC2=C(N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)N=C(N=C2N)Cl