Clotrimazole
目录号: A10234
克霉唑的作用针对真菌的分裂和生长。克霉唑改变真菌细胞壁的通透性，并抑制细胞内酶的活性。它特别抑制麦角甾醇和其他用于细胞膜生产的甾体的生物合成。
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生物活性
| Discription | Action of clotrimazole is against the division and growing of fungi.Clotrimazole alters the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. It specifically inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production. | |||||
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| Cell Research |
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产品信息
| 目录号 | A10234 |
|---|---|
| 分子式 | C22H17ClN2 |
| 分子量 | 344.84 |
| CAS号 | 23593-75-1 |
| SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 9 mg/mL (26.09 mM) | |
| Water | Insoluble | ||
| Ethanol | 59 mg/mL (171.09 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29 mL | 144.99 mL | 289.99 mL |
| 0.5 mM | 5.8 mL | 29 mL | 58 mL |
| 1 mM | 2.9 mL | 14.5 mL | 29 mL |
| 5 mM | 0.58 mL | 2.9 mL | 5.8 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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