Clozapine N-oxide
目录号: A15048
5-HT1C receptor 拮抗剂
Clozapine N-oxide 是 Clozapine 的一个主要代谢物,已在体外实验中观察到其能够降低 SR-2A (5-HT2 血清素受体) 密度。
Discription | Clozapine N-oxide is a major metabolite of Clozapine noted to decrease SR-2A (5-HT2 serotonin receptor) density in vitro. |
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目录号 | A15048 |
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分子式 | C18H19ClN4O |
分子量 | 342.82 |
CAS号 | 34233-69-7 |
SMILES | C[N+]1(CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl)[O-] |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 63 mg/mL (183.77 mM) | |
Water | 63 mg/mL (183.77 mM) | ||
Ethanol | 7 mg/mL (20.41 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.17 mL | 145.85 mL | 291.7 mL |
0.5 mM | 5.83 mL | 29.17 mL | 58.34 mL |
1 mM | 2.92 mL | 14.58 mL | 29.17 mL |
5 mM | 0.58 mL | 2.92 mL | 5.83 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2