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Clozapine是一种有效的5-HT1C受体拮抗剂，作用于5-HT刺激的磷酸肌醇水解。
靶点信息
| 5-HT2 | ||||
| In vitro | DMSO | 59 mg/mL (180.52 mM) | |
| Water | Insoluble | ||
| Ethanol | 29 mg/mL (88.73 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.6 mL | 153 mL | 306 mL |
| 0.5 mM | 6.12 mL | 30.6 mL | 61.2 mL |
| 1 mM | 3.06 mL | 15.3 mL | 30.6 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.12 mL |
*The above data is based on the productmolecular weight 326.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10236 |
|---|---|
| M. Wt | 326.8 |
| Formula | C18H19ClN4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 5786-21-0 |
| Synonyms | Clozaril, Fazaclo, HF 1854, Iprox, Klozapol, Leponex |
| SMILES | CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl |
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