Zegocractin (CM-4620)
目录号: A19452
CRAC 抑制剂
CM-4620 是一种钙释放激活的钙通道(CRAC)抑制剂,对 Orai1/STIM1 和 Orai2/STIM1 通道的 IC50 分别为 119 nM 和 895 nM。
Discription | CM-4620 is a calcium-release activated calcium-channel (CRAC) inhibitor, with IC50s of 119, 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively. |
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目录号 | A19452 |
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分子式 | C19H11ClF3N3O3 |
分子量 | 421.76 |
CAS号 | 1713240-67-5 |
SMILES | O=C(NC1=NC=C(C2=C(Cl)C=C(OC(F)(F)O3)C3=C2)N=C1)C4=C(C)C=CC=C4F |
其他名称 | CM4620, CM 4620 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 92 mg/mL (218.13 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.71 mL | 118.55 mL | 237.1 mL |
0.5 mM | 4.74 mL | 23.71 mL | 47.42 mL |
1 mM | 2.37 mL | 11.86 mL | 23.71 mL |
5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2