CMPD101
目录号: A19795
GRK2/GRK3 inhibitor
CMPD101 是一种新型的膜渗透性小分子抑制剂,能够抑制 GRK2 和 GRK3,其半抑制浓度(IC50)分别为 18 nM 和 5.4 nM。CMPD101 还能抑制 ROCK-2 和 PKCα(IC50 分别为 1.4 μM 和 8.1 μM)。
Discription | CMPD101, is a novel membrane-permeable, small-molecule inhibitor of both GRK2 and GRK3 with IC50s of 18 nM and 5.4 nM. CMPD101 also inhibits ROCK-2 and PKCα (IC50s=1.4 μM and 8.1 μM, respectively). | ||
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目录号 | A19795 |
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分子式 | C24H21F3N6O |
分子量 | 466.46 |
CAS号 | 865608-11-3 |
SMILES | O=C(C1=CC(NCC2=NN=C(C3=CC=NC=C3)N2C)=CC=C1)NCC4=CC=CC=C4C(F)(F)F |
其他名称 | CMPD 101, CMPD-101 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2