Combretastatin A4

Name: Combretastatin A4
SKU: A12601
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A12601

Combretastatin A4 是一种抗肿瘤、抗血管生成和抗转移剂，具有体外和体内活性。Combretastatin A4 是一种微管靶向剂，与 β-tubulin 结合，结合常数（Kd）为 0.4 μM。

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Grouped product items
规格	价格	库存
5mg	¥385.00	现货
10mg	¥210.00	现货
25mg	¥350.00	现货
50mg	¥630.00	现货
100mg	¥1,120.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Combretastatin A4 is an antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12601
分子式	C18H20O5
分子量	316.35
CAS号	117048-59-6
SMILES	COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O
其他名称	CRC 87-09, NSC 817373
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	58 mg/mL (183.34 mM)
	Water	Insoluble
	Ethanol	Warmed: 31 mg/mL (97.99 mM)
In vivo	5% DMSO+50% PEG 300+ddH2O	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.61 mL	158.05 mL	316.11 mL
0.5 mM	6.32 mL	31.61 mL	63.22 mL
1 mM	3.16 mL	15.81 mL	31.61 mL
5 mM	0.63 mL	3.16 mL	6.32 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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