Compstatin
Primates' C3 Inhibitor
Primates' C3 Inhibitor
Discription | Compstatin, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin inhibits only the activation of primates' complement system. Compstatin exhibits IC50 values of 63 μM and 12 μM for classical and alterative complement pathway, respectively. |
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目录号 | A22732 |
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分子式 | C66H99N23O17S2 |
分子量 | 1550.77 |
CAS号 | 206645-99-0 |
Sequence | Ile-Cys-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys12) |
Sequence shortening | ICVVQDWGHHRCT-NH2 (Disulfide bridge: Cys2-Cys12) |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2