Corin
目录号: A19548
LSD1 inhibitor
Corin 是一种同时抑制组蛋白赖氨酸特异性去甲基化酶(LSD1)和组蛋白去乙酰化酶(HDAC)的双重抑制剂,其对 LSD1 的不可逆抑制常数(Ki(inact))为 110 nM,对 HDAC1 的半抑制浓度(IC50)为 147 nM。
Discription | Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1. |
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目录号 | A19548 |
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分子式 | C26H28N4O2 |
分子量 | 428.53 |
CAS号 | 1808113-09-8 |
SMILES | O=C(NC1=CC=C([C@H]2[C@H](N)C2)C=C1)CCCC3=CC=C(C(NC4=CC=CC=C4N)=O)C=C3 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2