CP-640186
目录号: A13134
acetyl-CoA carboxylase inhibitor
CP-640186 是一种非选择性异构酶乙酰辅酶A羧化酶（ACC）抑制剂，对大鼠肝脏 ACC1 和大鼠骨骼肌 ACC2 的 IC50 分别为 53 nM 和 61 nM；与 CP-610431 相比，具有改善的代谢稳定性。
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生物活性
| Discription | CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431. | |||||
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| Cell Research |
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产品信息
| 目录号 | A13134 |
|---|---|
| 分子式 | C30H35N3O3 |
| 分子量 | 485.62 |
| CAS号 | 591778-68-6 |
| SMILES | C1C[C@H](CN(C1)C2CCN(CC2)C(=O)C3=C4C=CC=CC4=CC5=CC=CC=C53)C(=O)N6CCOCC6 |
| 其他名称 | CP 640186, CP640186 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 91 mg/mL (187.38 mM) | |
| Water | Insoluble | ||
| Ethanol | 91 mg/mL (187.38 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.59 mL | 102.96 mL | 205.92 mL |
| 0.5 mM | 4.12 mL | 20.59 mL | 41.18 mL |
| 1 mM | 2.06 mL | 10.3 mL | 20.59 mL |
| 5 mM | 0.41 mL | 2.06 mL | 4.12 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 591778-68-6 | 591778-68-6 供应商 | 591778-68-6 花费 | 591778-68-6 生产商 | 订购 591778-68-6 | 591778-68-6 代理商