CPI-203
CPI203 是一种新型的强效、选择性且细胞渗透性的抑制剂,针对 溴结构域和额外末端 (BET) 家族蛋白 BRD4,在 BRD4 α-screen 测试中的 IC50 约为 37 nM。
Discription | CPI203 is a novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 with an IC50 of ~37 nM (BRD4 α-screen assay). |
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目录号 | A13068 |
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分子式 | C19H18ClN5OS |
分子量 | 399.9 |
CAS号 | 1446144-04-2 |
SMILES | CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)N)C4=CC=C(C=C4)Cl)C |
其他名称 | CPI203 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 78 mg/mL (195.04 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (12.5 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.01 mL | 125.03 mL | 250.06 mL |
0.5 mM | 5 mL | 25.01 mL | 50.01 mL |
1 mM | 2.5 mL | 12.5 mL | 25.01 mL |
5 mM | 0.5 mL | 2.5 mL | 5 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2