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CRT0066101 is a PRKDs inhibitor. CRT0066101 suppressed the proliferation and migration of four bladder cancer cell lines in vitro. CRT0066101 blocked tumor growth in a mouse flank xenograft model of bladder cancer.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.17 mL | 145.85 mL | 291.69 mL |
| 0.5 mM | 5.83 mL | 29.17 mL | 58.34 mL |
| 1 mM | 2.92 mL | 14.58 mL | 29.17 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.83 mL |
*The above data is based on the productmolecular weight 342.827. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22539 |
|---|---|
| M. Wt | 342.827 |
| Formula | C18H19ClN4O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 956121-30-5 |
| Synonyms | CRT0066101 HCl, CRT-0066101, CRT 0066101, CRT0066101 free base |
| SMILES | OC1=CC=C(Cl)C=C1C2=NC(NC[C@H](N)CC)=C3C=CC=CC3=N2 |
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