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Cucurbitacin B是一种天然的三萜类化合物，以其强大的抗癌活性而闻名，研究表明该化合物抑制JAK/STAT3途径。也是一种有效的微管聚合抑制剂。
靶点信息
| Microtubule | ||||
| In vitro | DMSO | 94 mg/mL (168.24 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 47 mg/mL (84.12 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.9 mL | 89.49 mL | 178.99 mL |
| 0.5 mM | 3.58 mL | 17.9 mL | 35.8 mL |
| 1 mM | 1.79 mL | 8.95 mL | 17.9 mL |
| 5 mM | 0.36 mL | 1.79 mL | 3.58 mL |
*The above data is based on the productmolecular weight 558.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14665 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 558.7 |
| Formula | C32H46O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 6199-67-3 |
| SMILES | CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)C)C)C)O)O |
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