CUDC-305 (DEBIO-0932 )

Name: CUDC-305 (DEBIO-0932 )
SKU: A12648
Price: 385 CNY
Rating: 5 (2 reviews)

目录号: A12648

HSP90 抑制剂

2 篇发表文献

Debio 0932 是一种新型的热休克蛋白 90（HSP90）抑制剂，对 HSP90 alpha/beta 有很强的亲和力，具有高的口服生物利用度和针对广泛癌细胞系的强大抗增殖活性（平均 IC50 为 220 nmol/L），包括许多对标准治疗（SOC）药物具有抗性的非小细胞肺癌（NSCLC）细胞系。

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Grouped product items
规格	价格	库存
2mg	¥385.00	现货
5mg	¥735.00	现货
10mg	¥1,155.00	现货
25mg	¥2,415.00	现货
50mg	¥3,815.00	现货
100mg	¥7,455.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用CUDC-305 (DEBIO-0932 )发表的2篇文献

Ozlem Kaplan, .et al. , Med Oncol, 2024, Jul 3;41(8):194 PMID: 38958814

Aykut Ozgur, .et al. , Mol Biol Rep, 2021, Apr;48(4):3439-3449 PMID: 33999319

生物活性

Discription

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12648
分子式	C22H30N6O2S
分子量	442.58
CAS号	1061318-81-7
SMILES	CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4
其他名称	Debio0932; CUDC305
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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