CUDC-907 (Fimepinostat)

Name: CUDC-907 (Fimepinostat)
SKU: A11153
Price: 210 CNY
Rating: 5 (3 reviews)

目录号: A11153

PI3K/HDAC 抑制剂

3 篇发表文献

CUDC-907（Fimepinostat）是一种小分子抑制剂，能够同时针对PI3K和HDAC。CUDC-907比单一的PI3K抑制剂、HDAC抑制剂或这两种单一药物的最大耐受剂量组合更有效。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥630.00	现货
25mg	¥1,260.00	现货
50mg	¥2,240.00	现货
100mg	¥3,710.00	现货
500mg	¥8,015.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用CUDC-907 (Fimepinostat)发表的3篇文献

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Caner Gunayd?n, .et al. , Immunopharmacol Immunotoxicol, 2022, Jun;44(3):447-455 PMID: 35291899

Chie Ishikawa, .et al. , Eur J Haematol, 2020, Eur J Haematol PMID: 32780889

生物活性

Discription

CUDC-907 (Fimepinostat) is a single small molecule inhibitor that targets both PI3K and HDAC. CUDC-907 is more efficacious than either a single PI3K or HDAC inhibitor reference compound or a combination of the two single agents at maximally tolerated doses.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11153
分子式	C23H24N8O4S
分子量	508.6
CAS号	1339928-25-4
SMILES	CN(CC1=CC2=C(S1)C(=NC(=N2)C3=CN=C(C=C3)OC)N4CCOCC4)C5=NC=C(C=N5)C(=O)NO
其他名称	CUDC907
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	87 mg/mL (171.07 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.66 mL	98.31 mL	196.62 mL
0.5 mM	3.93 mL	19.66 mL	39.32 mL
1 mM	1.97 mL	9.83 mL	19.66 mL
5 mM	0.39 mL	1.97 mL	3.93 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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