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CX-4945 sodium salt是一种有效的选择性ATP竞争性小分子蛋白激酶CK2抑制剂,对重组人CK2α的Ki和IC50分别为0.38和1 nM。
In vitro | DMSO | 65 mg/mL (174.84 mM) | |
Water | 65 mg/mL (174.84 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.9 mL | 134.5 mL | 269 mL |
0.5 mM | 5.38 mL | 26.9 mL | 53.8 mL |
1 mM | 2.69 mL | 13.45 mL | 26.9 mL |
5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
*The above data is based on the productmolecular weight 371.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16234 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 371.75 |
Formula | C19H11ClN3NaO2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1309357-15-0 |
Synonyms | Silmitasertib sodium salt |
SMILES | [O-]C(C1=CC=C2C(N=C(NC3CC(Cl)CCC3)C4=C2C=NC=C4)=C1)=O |
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