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CX-6258 hydrochloride hydrate是一种有效的，口服有效的Pim 1/2/3激酶（IC50 = 5 nM/25 nM/16 nM）抑制剂，具有出色的生化效能和激酶选择性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.36 mL | 96.82 mL | 193.64 mL |
| 0.5 mM | 3.87 mL | 19.36 mL | 38.73 mL |
| 1 mM | 1.94 mL | 9.68 mL | 19.36 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.87 mL |
*The above data is based on the productmolecular weight 516.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15055 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 516.42 |
| Formula | C26H27Cl2N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1353858-99-7 |
| Synonyms | CX6258 hydrochloride hydrate, CX 6258 hydrochloride hydrate |
| SMILES | CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)C=C4C5=C(C=CC(=C5)Cl)NC4=O.O.Cl |
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