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CXD101 is a class I-selective HDAC inhibitor (HDAC1 (IC50, 63 nM), HDAC2 (IC50, 570 nM), HDAC3 (IC50, 550 nM). CXD101 has no activity against HDAC class II.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.78 mL | 123.91 mL | 247.82 mL |
| 0.5 mM | 4.96 mL | 24.78 mL | 49.56 mL |
| 1 mM | 2.48 mL | 12.39 mL | 24.78 mL |
| 5 mM | 0.5 mL | 2.48 mL | 4.96 mL |
*The above data is based on the productmolecular weight 403.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12253 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 403.52 |
| Formula | C24H29N5O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 934828-12-3 |
| Synonyms | CXD 101, CXD-101 |
| SMILES | O=C(NC1=C(N)C=CC=C1)C2=CC=C(C3CCN(CC4=CN(C)N=C4C)CC3)C=C2 |
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