Cycloheximide (Actidione)
环己酰胺(又称为放线菌酮)被用作一种选择性抗生素。它通过与80S核糖体结合,抑制腐生真菌真核生物的蛋白质合成(依赖DNA的RNA),而对皮肤癣菌和系统性真菌无效。
Discription | Cycloheximide (also known as actidione) is used as an selective antibiotic. It inhibits the protein synthesis (DNA-dependent RNA) of saprobic fungi eukaryotes. by binding with the 80S ribosome, while inactive against dermatophytes and systemic fungi. |
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目录号 | A10036 |
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分子式 | C15H23NO4 |
分子量 | 281.4 |
CAS号 | 66-81-9 |
SMILES | C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 48 mg/mL (170.61 mM) | |
Water | 13 mg/mL (46.2 mM) | ||
Ethanol | 48 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.54 mL | 177.68 mL | 355.37 mL |
0.5 mM | 7.11 mL | 35.54 mL | 71.07 mL |
1 mM | 3.55 mL | 17.77 mL | 35.54 mL |
5 mM | 0.71 mL | 3.55 mL | 7.11 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2