Momelotinib (Cyt387)

Name: Momelotinib (Cyt387)
SKU: A10263
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A10263

JAK 抑制剂

2 篇发表文献

CYT387 是一种抑制剂，针对 Janus kinases JAK1 和 JAK2，作为 ATP 竞争剂，其 IC50 值分别为 11 nM 和 18 nM。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥385.00	现货
10mg	¥595.00	现货
25mg	¥1,085.00	现货
50mg	¥1,855.00	现货
100mg	¥2,940.00	现货
200mg	¥4,515.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Momelotinib (Cyt387)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Momelotinib (Cyt387)发表的2篇文献

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Alex Bainbridge, .et al. , Nucleic Acids Research, 2020, April

生物活性

Discription

CYT387 is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10263
分子式	C23H22N6O2
分子量	414.5
CAS号	1056634-68-4
SMILES	C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	67 mg/mL (161.65 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40%PEG 300+ 3% Tween80 + ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.13 mL	120.63 mL	241.25 mL
0.5 mM	4.83 mL	24.13 mL	48.25 mL
1 mM	2.41 mL	12.06 mL	24.13 mL
5 mM	0.48 mL	2.41 mL	4.83 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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