CYT997 (Lexibulin)

Name: CYT997 (Lexibulin)
SKU: A10264

目录号: A10264

Microtubule 抑制剂

CYT997 (Lexibulin) Chemical Structure

CAS NO. 917111-44-5

CYT997 (Lexibulin)是一种新型的抗癌血管分裂剂(VDA)。在体外，CYT997被证明可有效抑制血管内皮生长因子刺激的人脐静脉内皮细胞（IC（50）3.7±1.8 nM）的增殖，并在100 nM时引起明显的形态变化，包括膜起泡。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
50 mg	￥ 2,800.00
100 mg	￥ 4,900.00
10mM * 1mL in DMSO	￥ 903.00

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产品详情

生物活性

靶点信息

Microtubules (cancer cell lines)
10 nM-100 nM

溶解度 *

In vitro	DMSO	77 mg/mL (177.2 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (41.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.01 mL	115.07 mL	230.15 mL
0.5 mM	4.6 mL	23.01 mL	46.03 mL
1 mM	2.3 mL	11.51 mL	23.01 mL
5 mM	0.46 mL	2.3 mL	4.6 mL

*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10264
作用机制	Inhibitor (抑制剂)
M. Wt	434.5
Formula	C24H30N6O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	917111-44-5
Synonyms	CYT-997, Lexibulin
SMILES	CCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC