CYT997 (Lexibulin)

Name: CYT997 (Lexibulin)
SKU: A10264
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A10264

Microtubule 抑制剂

CYT997 是一种新型的抗癌血管破坏剂（VDA）。在体外实验中，CYT997 被证明能强效抑制受血管内皮生长因子刺激的人脐静脉内皮细胞的增殖（IC(50) 3.7 ± 1.8 nM），并在 100 nM 的浓度下引起显著的形态学变化，包括细胞膜起泡。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥525.00	现货
10mg	¥945.00	现货
25mg	¥2,170.00	现货
50mg	¥2,765.00	现货
100mg	¥4,865.00	现货
200mg	¥7,875.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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Data Sheet

SDS

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生物活性

Discription

CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ?? 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10264
分子式	C24H30N6O2
分子量	434.5
CAS号	917111-44-5
SMILES	CCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (177.2 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (41.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.01 mL	115.07 mL	230.15 mL
0.5 mM	4.6 mL	23.01 mL	46.03 mL
1 mM	2.3 mL	11.51 mL	23.01 mL
5 mM	0.46 mL	2.3 mL	4.6 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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