Cytarabine hydrochloride
目录号: A17692
nucleoside analog
Cytarabine hydrochloride,一种核苷类似物,能引起S期细胞周期阻滞并抑制DNA聚合酶。Cytarabine抑制DNA合成的IC50为16 nM。
Discription | Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. | |||||
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Targets |
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Cell Research |
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目录号 | A17692 |
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分子式 | C9H14ClN3O5 |
分子量 | 279.68 |
CAS号 | 69-74-9 |
SMILES | O=C1N=C(N)C=CN1[C@H]2[C@H]([C@@H]([C@@H](CO)O2)O)O.Cl |
其他名称 | Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 49 mg/mL (175.2 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.76 mL | 178.78 mL | 357.55 mL |
0.5 mM | 7.15 mL | 35.76 mL | 71.51 mL |
1 mM | 3.58 mL | 17.88 mL | 35.76 mL |
5 mM | 0.72 mL | 3.58 mL | 7.15 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2