CZC54252 hydrochloride
目录号: A15510
LRRK2 抑制剂
CZC-54252 是一种强效的 LRRK2 抑制剂,其 IC50 分别为 1.28 nM 和 1.85 nM,针对野生型和 G2019S LRRK2。
Discription | CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively. |
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目录号 | A15510 |
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分子式 | C22H25ClN6O4S.HCl |
分子量 | 541.45 |
CAS号 | 1191911-27-9 |
SMILES | COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl |
其他名称 | CZC-54252 hydrochloride, CZC 54252 hydrochloride |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 85 mg/mL (168.32 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.47 mL | 92.34 mL | 184.69 mL |
0.5 mM | 3.69 mL | 18.47 mL | 36.94 mL |
1 mM | 1.85 mL | 9.23 mL | 18.47 mL |
5 mM | 0.37 mL | 1.85 mL | 3.69 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2