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D4476是酪蛋白激酶1的细胞渗透抑制剂。
靶点信息
| CK1 from Schizosaccharomyces pombe | CK1δ | ALK5 | ||
| 200 nM | 300 nM | 500 nM |
| In vitro | DMSO | 71 mg/mL (178.2 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.1 mL | 125.5 mL | 251 mL |
| 0.5 mM | 5.02 mL | 25.1 mL | 50.2 mL |
| 1 mM | 2.51 mL | 12.55 mL | 25.1 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
*The above data is based on the productmolecular weight 398.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13949 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 398.41 |
| Formula | C23H18N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 301836-43-1 |
| Synonyms | D 4476, D-4476 |
| SMILES | C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
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