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Dabigatran etexilate mesylate是达比加群的口服活性前药。达比加群是一种可逆的选择性直接凝血酶抑制剂（DTI），Ki值为4.5 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.82 mL | 69.08 mL | 138.15 mL |
| 0.5 mM | 2.76 mL | 13.82 mL | 27.63 mL |
| 1 mM | 1.38 mL | 6.91 mL | 13.82 mL |
| 5 mM | 0.28 mL | 1.38 mL | 2.76 mL |
*The above data is based on the productmolecular weight 723.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15057 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 723.84 |
| Formula | C35H45N7O8S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 872728-81-9 |
| Synonyms | Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate |
| SMILES | CCCCCCOC(=O)N=C(C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)N.CS(=O)(=O)O |
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