Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Name: Dapagliflozin ((2S)-1,2-propanediol, hydrate)
SKU: A17687
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A17687

SGLT2 抑制剂

达格列净（(2S)-1,2-丙二醇，水合物），一种用于治疗糖尿病（DM）的新型药物，是一种竞争性钠/葡萄糖共转运蛋白2（SGLT2）抑制剂，其作用机制是导致葡萄糖排泄到尿液中。

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Dapagliflozin ((2S)-1,2-propanediol, hydrate)

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥245.00	现货
25mg	¥280.00	现货
50mg	¥350.00	现货
100mg	¥455.00	现货
500mg	¥1,155.00	现货
*10mM 1mL in DMSO**	¥175.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of drug used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine.

产品信息

目录号	A17687
分子式	C24H35ClO9
分子量	502.98
CAS号	960404-48-2
SMILES	O[C@H]1[C@H](C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O.C[C@H](O)CO.O
其他名称	BMS-512148 (2S)-1,2-propanediol, hydrate
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (182.91 mM)
	Water	Insoluble
	Ethanol	92 mg/mL (182.91 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.88 mL	99.41 mL	198.82 mL
0.5 mM	3.98 mL	19.88 mL	39.76 mL
1 mM	1.99 mL	9.94 mL	19.88 mL
5 mM	0.4 mL	1.99 mL	3.98 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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