Signaling Pathway
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| Discription | Dasatinib hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of <1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM. | ||
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| Targets |
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| 目录号 | A15060 |
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| 分子式 | C22H27Cl2N7O2S |
| 分子量 | 524.47 |
| CAS号 | 854001-07-3 |
| SMILES | CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=NC(=NC(=C3)N4CCN(CC4)CCO)C.Cl |
| 其他名称 | BMS-354825 hydrochloride, Sprycel hydrochloride, BMS354825 hydrochloride, BMS 354825 hydrochloride |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 85 mg/mL (162.06 mM) | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.07 mL | 95.33 mL | 190.67 mL |
| 0.5 mM | 3.81 mL | 19.07 mL | 38.13 mL |
| 1 mM | 1.91 mL | 9.53 mL | 19.07 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
