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Dasatinib Monohydrate是一种新型，有效且多靶点的抑制剂，靶向Abl，Src和c-Kit，IC50分别<1 nM，0.8 nM和79 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.76 mL | 98.81 mL | 197.62 mL |
| 0.5 mM | 3.95 mL | 19.76 mL | 39.52 mL |
| 1 mM | 1.98 mL | 9.88 mL | 19.76 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16320 |
|---|---|
| M. Wt | 506.02 |
| Formula | C22H28ClN7O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 863127-77-9 |
| Synonyms | BMS354825 |
| SMILES | CC1=C(/N=C(O)/C(S2)=CN=C2NC3=CC(N4CCN(CCO)CC4)=NC(C)=N3)C(Cl)=CC=C1.O |
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