DB04760
目录号: A18548
MMP-13 抑制剂
DB04760(化合物4)是一种效力强大、高度选择性的、非锌螯合的MMP-13抑制剂,其IC50为8 nM。DB04760显著减少紫杉醇的神经毒性,并具有抗癌活性。
Discription | DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity. | ||
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目录号 | A18548 |
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分子式 | C22H20F2N4O2 |
分子量 | 410.42 |
CAS号 | 544678-85-5 |
SMILES | FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C |
其他名称 | DB 04760, DB-04760 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2