DC41SMe

Name: DC41SMe
SKU: A20158
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A20158

DNA alkylator

DC41SMe，一种DC1的衍生物，在Ramos、Namalwa 和 HL60/s 细胞中显示出细胞毒性，IC50 范围在18-25 pM之间。DC1 是 CC-1065 的简化类似物，是一种针对癌症治疗的靶向性抗体偶联物，包含细胞毒性的DNA烷化剂。

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Grouped product items
规格	价格	库存
1mg	¥2,205.00	现货
5mg	¥6,685.00	现货
10mg	¥11,165.00	现货
25mg	¥22,155.00	现货
50mg	¥29,225.00	现货
100mg	¥40,565.00	现货
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Data Sheet

SDS

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生物活性

Discription

DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20158
分子式	C38H36ClN5O4S2
分子量	726.31
CAS号	1354787-71-5
SMILES	O=C(C(N1)=CC2=C1C=CC(NC(CCC(SSC)(C)C)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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