DCC-2036 (Rebastinib)

Name: DCC-2036 (Rebastinib)
SKU: A11200
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A11200

Bcr-Abl 抑制剂

1 篇发表文献

DCC-2036 是一种口服生物利用度高的小分子抑制剂，能够抑制多种酪氨酸激酶，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥385.00	现货
10mg	¥630.00	现货
25mg	¥1,225.00	现货
50mg	¥1,785.00	现货
100mg	¥2,730.00	现货
200mg	¥4,130.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用DCC-2036 (Rebastinib)发表的1篇文献

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

生物活性

Discription

DCC-2036 is an orally bioavailable small-molecule inhibitor of multiple tyrosine kinases with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11200
分子式	C30H28FN7O3
分子量	553.59
CAS号	1020172-07-9
SMILES	CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
其他名称	DCC2036
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	103 mg/mL (186.05 mM)
	Water	Insoluble
	Ethanol	15 mg/mL (27.09 mM)
In vivo	0.5% CMC+0.25% Tween 80	15 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.06 mL	90.32 mL	180.64 mL
0.5 mM	3.61 mL	18.06 mL	36.13 mL
1 mM	1.81 mL	9.03 mL	18.06 mL
5 mM	0.36 mL	1.81 mL	3.61 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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