DCC-2618
目录号: A15062
C-Kit/PDGFR 抑制剂
DCC-2618 是一种小分子抑制剂，针对 c-Kit 和 PDGFR，其 IC50 分别为 c-Kit/PDGFRα/PDGFRβ 的 6 nM/30 nM/13 nM。
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生物活性
| Discription | DCC-2618 is a small molecule inhibitor of c-Kit and PDGFR with IC50s of 6 nM/30 nM/13 nM for c-Kit/PDGFRα/PDGFRβ respectively. |
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产品信息
| 目录号 | A15062 |
|---|---|
| 分子式 | C26H21F2N5O3 |
| 分子量 | 489.47 |
| CAS号 | 1225278-16-9 |
| SMILES | CN1C=C(C=N1)C2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=CC=C5)F |
| 其他名称 | DCC2618, DCC 2618 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 83 mg/mL (169.57 mM) | |
| Water | Insoluble | ||
| Ethanol | 8 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.43 mL | 102.15 mL | 204.3 mL |
| 0.5 mM | 4.09 mL | 20.43 mL | 40.86 mL |
| 1 mM | 2.04 mL | 10.22 mL | 20.43 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.09 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1225278-16-9 | 1225278-16-9 供应商 | 1225278-16-9 花费 | 1225278-16-9 生产商 | 订购 1225278-16-9 | 1225278-16-9 代理商