DCPIB
目录号: A19268
VRAC inhibitor
DCPIB 是一种选择性、可逆的、高效的体积调节阴离子通道(VRAC)抑制剂,能够依赖电压地激活钾通道 TREK1 和 TRAAK,并抑制 TRESK、TASK1 和 TASK3(各自的 IC50 值分别为 0.14、0.95、50.72 微米)。
Discription | DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). |
---|
目录号 | A19268 |
---|---|
分子式 | C22H28Cl2O4 |
分子量 | 427.36 |
CAS号 | 82749-70-0 |
SMILES | O=C(O)CCCOC1=CC2=C(C(C(C3CCCC3)(CCCC)C2)=O)C(Cl)=C1Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2