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DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.99 mL | 79.93 mL | 159.87 mL |
| 0.5 mM | 3.2 mL | 15.99 mL | 31.97 mL |
| 1 mM | 1.6 mL | 7.99 mL | 15.99 mL |
| 5 mM | 0.32 mL | 1.6 mL | 3.2 mL |
*The above data is based on the productmolecular weight 625.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21813 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 625.51 |
| Formula | C30H33Cl2F3N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1780303-76-5 |
| SMILES | CC1=C(C=C(C=C1)NC(C2=CC=C(C(C(F)(F)F)=C2)CN3CCN(CC3)CC)=O)OC4=CC(C5)=C(C=C4)NC5=O.Cl.Cl |
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