Debio-1347 (CH5183284)

Name: Debio-1347 (CH5183284)
SKU: A14415
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A14415

FGFR1/2/3 抑制剂

Debio-1347 是一种口服生物可利用的抑制剂，针对成纤维细胞生长因子受体亚型 1（FGFR-1）、2（FGFR-2）和 3（FGFR-3），具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥840.00	现货
50mg	¥1,330.00	现货
100mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription

Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14415
分子式	C20H16N6O
分子量	356.38
CAS号	1265229-25-1
SMILES	CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
其他名称	Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	70 mg/mL (196.41 mM)
	Water	Insoluble
	Ethanol	Warmed: 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.06 mL	140.3 mL	280.6 mL
0.5 mM	5.61 mL	28.06 mL	56.12 mL
1 mM	2.81 mL	14.03 mL	28.06 mL
5 mM	0.56 mL	2.81 mL	5.61 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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