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Decitabine是一种次甲基化剂,它通过抑制DNA甲基转移酶来使DNA次甲基化。
靶点信息
DNA methylation (HL-60, KG1a cells) | ||||
In vitro (25°C) | DMSO | 44 mg/mL (192.8 mM) | |
Water | 10 mg/mL (43.81 mM) | ||
Ethanol | Insoluble | ||
In vivo | water | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 43.82 mL | 219.11 mL | 438.21 mL |
0.5 mM | 8.76 mL | 43.82 mL | 87.64 mL |
1 mM | 4.38 mL | 21.91 mL | 43.82 mL |
5 mM | 0.88 mL | 4.38 mL | 8.76 mL |
*The above data is based on the productmolecular weight 228.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10292 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 228.2 |
Formula | C8H12N4O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 2353-33-5 |
Synonyms | Dacogen |
SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O |
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