Defactinib hydrochloride

目录号: A22003

FAK inhibitor

Defactinib hydrochloride

Defactinib hydrochloride Chemical Structure

CAS NO. 1073160-26-5

Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

库存: 现货

规格 价格 数量
5 mg
¥ 532.00
10 mg
¥ 910.00
50 mg
¥ 2,702.00
100 mg
¥ 5,411.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.28 mL 91.42 mL 182.83 mL
0.5 mM 3.66 mL 18.28 mL 36.57 mL
1 mM 1.83 mL 9.14 mL 18.28 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 546.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A22003
作用机制 Inhibitor (抑制剂)
M. Wt 546.95
Formula C20H22ClF3N8O3S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1073160-26-5
Synonyms VS-6063 hydrochloride, VS6063, VS 6063; PF 04554878 hydrochloride, PF-04554878, PF04554878
SMILES O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1.[H]Cl

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