Deferasirox

Name: Deferasirox
SKU: A10293
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A10293

Iron chelator

2 篇发表文献

Deferasirox 是一种合理设计的口服铁螯合剂，同时也是细胞色素P450 3A4诱导剂、细胞色素P450 2C8抑制剂和细胞色素P450 1A2抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥490.00	现货
50mg	¥770.00	现货
100mg	¥1,155.00	现货
500mg	¥2,940.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Deferasirox发表的2篇文献

Celine Moison, .et al. , Sci Adv, 2024, Mar 22;10(12):eadl4018 PMID: 38517966

Jamie L. Dombach, .et al. , PLoS Pathog, 2020, Dec; 16(12): e1009119 PMID: 33290418

生物活性

Discription	Deferasirox is a rationally-designed oral iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor.

产品信息

目录号	A10293
分子式	C21H15N3O4
分子量	373.36
CAS号	201530-41-8
SMILES	C1=C/C(=C\2/N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1
其他名称	ICL-670, ICL-670A, CGP-72670
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	64 mg/mL (171.42 mM)
	Water	Insoluble
	Ethanol	2 mg/mL
In vivo	5% DMSO+40% PEG 300+5%Tween 80 +50 % H2O	3.5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.78 mL	133.92 mL	267.84 mL
0.5 mM	5.36 mL	26.78 mL	53.57 mL
1 mM	2.68 mL	13.39 mL	26.78 mL
5 mM	0.54 mL	2.68 mL	5.36 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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