Deforolimus (Ridaforolimus)

Name: Deforolimus (Ridaforolimus)
SKU: A10295
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A10295

mTOR 抑制剂

Deforolimus（Ridaforolimus）是一种处于研究阶段的靶向性小分子抑制剂，其作用目标是蛋白质 mTOR。通过阻断 mTOR，可以在癌细胞中产生类似饥饿的效果，这种效果通过干扰细胞的生长、分裂、代谢和血管生成来实现。

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Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥490.00	现货
25mg	¥1,120.00	现货
50mg	¥2,030.00	现货
100mg	¥3,465.00	现货
*10mM 1mL in DMSO**	¥1,246.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Deforolimus (Ridaforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR. Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.

Targets

Target	Value

产品信息

目录号	A10295
分子式	C53H84NO14P
分子量	990.2
CAS号	572924-54-0
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC
其他名称	AP23573, MK-8669
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	196 mg/mL (197.93 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+5% Tween 80+50% H2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.1 mL	50.49 mL	100.99 mL
0.5 mM	2.02 mL	10.1 mL	20.2 mL
1 mM	1.01 mL	5.05 mL	10.1 mL
5 mM	0.2 mL	1.01 mL	2.02 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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