主页 /
PI3K / Akt / mTOR /
mTOR /
Deforolimus (Ridaforolimus)

Deforolimus (Ridaforolimus)

Name: Deforolimus (Ridaforolimus)
SKU: A10295

目录号: A10295

mTOR 抑制剂

Deforolimus (Ridaforolimus) Chemical Structure

CAS NO. 572924-54-0

Deforolimus (Ridaforolimus)是mTOR蛋白的研究目标靶向小分子抑制剂。阻断mTOR通过干扰细胞生长，分裂，代谢和血管生成，在癌细胞中产生饥饿样的效应。

库存：现货

规格	价格	数量
5 mg	￥ 385.00
10 mg	￥ 539.00
50 mg	￥ 2,072.00
100 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 1,246.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Deforolimus (Ridaforolimus)是mTOR蛋白的研究目标靶向小分子抑制剂。阻断mTOR通过干扰细胞生长，分裂，代谢和血管生成，在癌细胞中产生饥饿样的效应。

靶点信息

mTOR (HT-1080 cells)
0.2 nM

溶解度 *

In vitro (25°C)	DMSO	196 mg/mL (197.93 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+5% Tween 80+50% H2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.1 mL	50.49 mL	100.99 mL
0.5 mM	2.02 mL	10.1 mL	20.2 mL
1 mM	1.01 mL	5.05 mL	10.1 mL
5 mM	0.2 mL	1.01 mL	2.02 mL

*The above data is based on the productmolecular weight 990.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10295
作用机制	Inhibitor (抑制剂)
M. Wt	990.2
Formula	C53H84NO14P
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	572924-54-0
Synonyms	AP23573, MK-8669, MK8669
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC