DEL-22379
目录号: A15802
ERK 抑制剂
DEL-22379 是一种强效且选择性的 ERK 二聚体抑制剂，它能够抑制 ERK 二聚体 形成，而不影响 ERK 磷酸化，从而阻止由 RAS-ERK 通路 癌基因驱动的肿瘤发生。
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生物活性
| Discription | DEL-22379 is a potent and selective ERK Dimerization inhibitor that inhibits ERK Dimerization without affecting ERK phosphorylation, forestalls tumorigenesis driven by RAS-ERK pathway oncogenes. | ||
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产品信息
| 目录号 | A15802 |
|---|---|
| 分子式 | C26H28N4O3 |
| 分子量 | 444.55 |
| CAS号 | 181223-80-3 |
| SMILES | O=C1NC2=CC=C(NC(CCN3CCCCC3)=O)C=C2C1=CC4=CNC5=CC=C(OC)C=C54 |
| 其他名称 | DEL22379, DEL 22379 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 79 mg/mL (177.71 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.49 mL | 112.47 mL | 224.95 mL |
| 0.5 mM | 4.5 mL | 22.49 mL | 44.99 mL |
| 1 mM | 2.25 mL | 11.25 mL | 22.49 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 181223-80-3 | 181223-80-3 供应商 | 181223-80-3 花费 | 181223-80-3 生产商 | 订购 181223-80-3 | 181223-80-3 代理商